![]() The composition of ICF is discussed in Chapter 1. It constitutes two thirds of total body water or 40% of body weight. ICF is the water inside the cells in which all intracellular solutes are dissolved. ![]() 6-4), is quantitatively small and includes the cerebrospinal, pleural, peritoneal, and digestive fluids. A third body fluid compartment, the transcellular compartment (not shown in Fig. Approximately three fourths of the ECF is found in the interstitial compartment, and the remaining one fourth is found in the plasma. (The 60-40-20 rule is useful to know: 60% of body weight is water, 40% is ICF, and 20% is ECF.) ECF is further divided among two minor compartments: the interstitial fluid and the plasma. When expressed as percentage of body weight, 40% of body weight is in ICF (two thirds of 60%), and 20% of body weight is in ECF (one third of 60%). Approximately two thirds of total body water is in the ICF, and about one third is in the ECF. Total body water is distributed between two major compartments: intracellular fluid ( ICF) and extracellular fluid( ECF). ![]() The distribution of water among the body fluid compartments is shown in Figure 6-4. For example, in the absence of other explanations, a sudden weight loss of 3 kg reflects a loss of 3 kg (≈3 L) of total body water. The relationship between water content and body weight is clinically important because changes in body weight can be used to estimate changes in body water content. Water as a percentage of body weight is indicated for the major compartments. For these reasons, thin men have the highest percentage of body weight as water (≈70%) and obese women have the lowest percentage (≈50%).įigure 6–4 Body fluid compartments. Total body water is distributed between intracellular fluid and extracellular fluid. Women have lower percentages of water than men (because women have the higher percentage of adipose tissue). Water content of the body correlates inversely with fat content. The percentage of total body water varies, depending on gender and the amount of adipose tissue in the body. Water accounts for 50% to 70% of body weight, with an average value of 60% ( Fig. Discussion in this section includes the distribution of water in various compartments of the body the methods of measuring volumes of the body fluid compartments the differences in concentrations of major cations and anions among the compartments and the shifts of water that occur between the body fluid compartments when a physiologic disturbance occurs.ĭistribution of Water among the Body Fluids Water is the medium of the internal environment and constitutes a large percentage of the body weight.
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